A INFLUENZA A VIRUS HAVING INCREASED PATHOGENICITY AGAINST MOUSE

摘要

The present invention relates to influenza A virus having increased pathogenicity to a mouse, and a method for preparing a mouse model of influenza A virus infection using the same. The influenza A virus comprises a gene encoding proteins selected from a group comprising: a polymerase acidic protein; a polymerase basic protein; and a polymerase basic protein 2.