A sustained-release disintegrating solid preparation in the mouth, a method for producing the same, and a powder composition for use in the preparation method

摘要

An object of the present invention is to provide a sustained-release type disintegrating solid preparation having excellent disintegration and cohesiveness, a method for producing the same, and a powder composition for use in the above-described method. The present invention relates to an oral cavity sustained-release disintegrating solid preparation containing at least one kind of disintegrant and at least one water-soluble polymer and having an onset time of disintegration of not more than 40 seconds and an index showing cohesiveness of not less than 0.4, A powder composition comprising the disintegrating particle composition containing at least one kind of a disintegrant and at least one water-soluble polymer for use in the above-mentioned production method, and the like.