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MIRO SPORE FOR DETECTING TARGET BIO-MOLECULE DETECTING SYSTEM AND DETECTING METHOD USING THE SAME
MIRO SPORE FOR DETECTING TARGET BIO-MOLECULE DETECTING SYSTEM AND DETECTING METHOD USING THE SAME
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机译:用于目标生物分子检测系统的微孔检测及使用该方法的检测方法
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摘要
The present invention relates to a micro spore for detecting a target bio-molecule, and a detecting system and a detecting method using the micro spore. According to the present invention, the micro spore for detecting a target bio-molecule includes: a polynucleotide clotting part formed by clotting a plurality of encoded polynucleotides; an external membrane holding the polynucleotide clotting part therein; and a probe linker formed on the surface of the external membrane to be complementarily bound with a partial area of the target bio-molecule. The external membrane gets broken by external impulses in a state that the probe linker is coupled to the target bio-molecule such that the polynucleotide clotting part is exposed to the outside, the plurality of polynucleotides forming the polynucleotide clotting part get unclotted and discharged, and the target bio-molecule can be detected through sensing of the plurality of polynucleotides. Therefore, the present invention can exactly detect even a small amount of the target bio-molecule without amplifying the target bio-molecule, and also can minimize time and costs for test.
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