ANTIBODIES FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE-ASSOCIATED INFECTION AND DISEASE

摘要

Clostridium difficile bacteria and clostridium difficile infections resulting from infection by intestinal toxins produced by these bacteria and related disease conditions and pathologies, for example, reagents for treating clostridium difficile associated diarrhea, Compositions and methods of treatment are provided. In particular, an antibody or antigen-binding fragment thereof which specifically binds to toxin A and / or toxin B of clostridium difficile and neutralizes the activity of these toxins; A composition comprising these antibodies; And methods of using the antibodies and compositions.