Regioselective synthesis of alkyl EGCG derivatives

摘要

The present invention relates to a synthesis method for regioselective alkylation of ((-)-epigallocatechin gallate (-)-EGCG), and in the regioselective alkylation of the (-)-EGCG according to the present invention, EGCG is firstly acetylated and alkylated without directly alkylating EGCG, thereby producing 4-alkylated-EGCG with a high yield.