Composition for prevention and treatment of muscular disorder or improvement of muscular functions comprising Mori Cortex Radicis extract morusin or kuwanon G

摘要

The present invention relates to a composition for preventing or treating muscular diseases or improving muscular function comprising at least one selected from the group consisting of morusin, kuwanon G and Mori Cortex Radicis as an active ingredient . The present invention relates to a method for inhibiting mRNA expression of MuRF-1 and atrogin-1, which is involved in muscle protein degradation, an increase in protein expression of p-mTOR involved in muscle protein synthesis, And myogenin mRNA expression of MyoD, it has the effect of excellently enhancing muscle function. Further, since the present invention is a natural product, it can be safely used without side effects and can be used as medicines, foods, or cosmetics.