-9 A human fibroblast growth factor-9 mutant with high stability and use of the same

摘要

The present invention relates to a high-stability fibroblast growth factor-9 mutant and its use, and more particularly, to a high-stability fibroblast growth factor-9 mutant and its use. More specifically, A high-stability fibroblast growth factor-9 (FGF-9) mutant, a DNA base sequence encoding the FGF-9 mutant, an expression vector containing the DNA base sequence, A transformant transformed, a method for producing the FGF-9 mutant, and a composition comprising an FGF-9 mutant as an active ingredient. According to the present invention, the FGF-9 mutant of the present invention is excellent in heat stability and stability in an aqueous solution state, so that functional cosmetics which do not lose their activity unlike conventional natural FGF-9 products during distribution and storage, Wound cloning and hair growth, hair growth, and hair loss treatment.;