PI3 Heteroaryl derivatives or pharmaceutically acceptable salts thereof preparation method thereof and pharmaceutical composition for use in preventing or treating PI3 kinase related diseases

摘要

The present invention relates to a heteroaryl derivative or a pharmaceutically acceptable salt thereof, a process for producing the same, and a pharmaceutical composition for preventing or treating PI3 kinase-related diseases containing the same as an active ingredient. The heteroaryl derivative according to the present invention is excellent in the selective inhibition effect on PI3 kinase and thus can be used for the treatment of blood cancer, ovarian cancer, cervical cancer, breast cancer, colon cancer, liver cancer, stomach cancer, pancreatic cancer, colon cancer, peritoneal cancer, Cancer, such as prostate cancer, lung cancer, osteosarcoma, fibroid tumor, brain tumor, rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, type 1 diabetes, hyperthyroidism, myasthenia, Crohn's disease, ankylosing spondylitis, (COPD), rhinitis, asthma, chronic bronchitis, chronic pulmonary inflammatory disease, silicosis, pulmonary sarcoidosis, pleurisy, alveolitis, vasculitis, pneumonia, bronchopulmonary disease, anemia such as anemia, Sjogren's syndrome Such as respiratory diseases such as RTI ID = 0.0 PI3 / RTI kinase-related diseases.