首页> 外国专利> A METHOD FOR CANCER DIAGNOSTICS BY WAY OF LOGISTIC REGRESSION ANALYSIS OF PERIPHERAL BLOOD IMMUNITY

A METHOD FOR CANCER DIAGNOSTICS BY WAY OF LOGISTIC REGRESSION ANALYSIS OF PERIPHERAL BLOOD IMMUNITY

机译:外周血免疫力的Logistic回归分析方法对癌症的诊断方法

摘要

According to the present invention, a method for evaluating immunity of peripheral blood by using distribution difference of immune cells in cancer patient′s peripheral blood and normal person′s blood and providing information of cancer occurrence by using the same comprises the following steps: (A) analyzing cell size and degree of immune cells being wrinkled in peripheral blood and classifying lymphocytes; (B) dyeing markers of the lymphocytes in at least one combination of antibodies and analyzing distribution of the immune cells in cancer patient′s peripheral blood and normal person′s blood; (C) determining significant combination of significant markers which can exhibit sensitivity and specificity enough to enable a user to diagnose or classify a cancer patient and a normal person to determine cancer occurrence between a cancer patient and normal person; and (D) diagnosing cancer occurrence by measuring immunity per blood unit by using the marker without using a coefficient of a natural killer cell obtained by using a parenchymatous cell analyzer or a cell coefficient device.
机译:根据本发明,通过利用癌症患者的外周血和正常人的血液中的免疫细胞的分布差异来评估外周血的免疫力并通过使用其提供癌症发生信息的方法包括以下步骤:( A)分析外周血中起皱的免疫细胞的细胞大小和程度,并对淋巴细胞进行分类; (B)对至少一种抗体组合中的淋巴细胞进行染色,并分析免疫细胞在癌症患者外周血和正常人血液中的分布; (C)确定显着标志物的显着组合,所述显着标志物可以表现出足够的敏感性和特异性,以使用户能够诊断或分类癌症患者和正常人以确定癌症患者和正常人之间的癌症发生; (D)在不使用通过实质细胞分析仪或细胞系数装置获得的自然杀伤细胞系数的情况下,通过使用所述标记物通过测量每血液单位的免疫力来诊断癌症的发生。

著录项

  • 公开/公告号KR101847778B1

    专利类型

  • 公开/公告日2018-04-12

    原文格式PDF

  • 申请/专利权人 LEE JONG KYUN;

    申请/专利号KR20170068736

  • 发明设计人 LEE JONG KYUN;CHOI JOUNG BUM;

    申请日2017-06-02

  • 分类号G01N33/574;G01N15/14;G01N33/58;G06F19/26;

  • 国家 KR

  • 入库时间 2022-08-21 12:38:03

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