Since bio-pathways are individually and independently constructed using various bio-pathway description languages (KGML, SBML, BIOPAX, etc.) in various bio-pathway related organizations, the present invention effectively integrates and expands bio-pathways expressed in heterogeneous languages . To this end, the present invention comprises a first input module for receiving at least one bio-pathway; A language unification module for converting the at least one biopathway into a first language; A separation module for separating at least one or more biopathways converted into the first language into nodes or relationships; A standardization module for standardizing the node or relationship in standard terms and extracting attribute information related to the node or relationship from at least one or more biopathways separated in the form of the node or relationship; An integration module for integrating at least one or more biopathways separated by the node or relationship; A document knowledge module for generating extension information for expanding the integrated bio-pathway; And an extension module for expanding the integrated bio-pathway using the generated extension information.
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