首页> 外国专利> PM2 Novel Proteus mirabilis specific bacteriophage PM2 and antibacterial composition comprising the same

PM2 Novel Proteus mirabilis specific bacteriophage PM2 and antibacterial composition comprising the same

机译:PM2新型奇异变形杆菌特异性噬菌体PM2和包含该噬菌体的抗菌组合物

摘要

The present invention relates to a novel bacteriophage PM2 having a killing activity specific to Proteus mirabilis, a pharmaceutical composition for preventing or treating infectious diseases caused by Proteus mirabilis containing the bacteriophage, an antibiotic composition, , A disinfectant or detergent, and a method for preventing or treating infectious diseases caused by Proteus mirabilis comprising the step of administering the bacteriophage to an animal. The method for preventing or treating an infectious disease caused by Proteus mirabilis using the bacteriophage PM2 of the present invention has a very high specificity to Proteus mirabilis as compared with a chemical substance such as existing antibiotics, It has an advantage that it infects Mirabillis and proliferates more than 100 times in the Proteus mirabilis, so that it has excellent lytic activity and is strong against physicochemical stimulation. In addition, the bacteriophage PM2 of the present invention is not infected with any host other than bacteria such as human, animal, and plant, and thus has the advantage of solving problems of antibiotic resistant bacteria caused by abuse of antibiotics, residual antibiotics in food, have. Therefore, the bacteriophage PM2 of the present invention can be variously used in the field of prevention or treatment of infectious diseases caused by Proteus mirabilis, compositions for antibiosis, composition for feed addition, feed, disinfectant, or detergent.
机译:本发明涉及具有对奇异变形杆菌特异的杀灭活性的新型噬菌体PM2,用于预防或治疗由奇异变形杆菌引起的感染性疾病的药物组合物,抗生素组合物,消毒剂或去污剂以及预防方法或治疗由奇异变形杆菌引起的感染性疾病,包括将噬菌体施用于动物的步骤。与现有的抗生素等化学物质相比,使用本发明的噬菌体PM2来预防或治疗由奇异变形杆菌引起的传染病的方法对奇异变形杆菌具有非常高的特异性。优点是它能感染Mirabillis,并在Proteus mirabilis中增殖100倍以上,因此它具有出色的裂解活性,并且对理化刺激作用强。另外,本发明的噬菌体PM2不被除人,动物,植物等细菌以外的任何宿主感染,因此具有解决因滥用抗生素,食品中残留的抗生素而引起的抗生素抗性细菌的问题的优点。 ,有。因此,本发明的噬菌体PM2可以在预防或治疗由奇异变形杆菌引起的感染性疾病,抗微生物组合物,饲料添加组合物,饲料,消毒剂或去污剂中各种使用。

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