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PM2 Novel Proteus mirabilis specific bacteriophage PM2 and antibacterial composition comprising the same
PM2 Novel Proteus mirabilis specific bacteriophage PM2 and antibacterial composition comprising the same
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机译:PM2新型奇异变形杆菌特异性噬菌体PM2和包含该噬菌体的抗菌组合物
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摘要
The present invention relates to a novel bacteriophage PM2 having a killing activity specific to Proteus mirabilis, a pharmaceutical composition for preventing or treating infectious diseases caused by Proteus mirabilis containing the bacteriophage, an antibiotic composition, , A disinfectant or detergent, and a method for preventing or treating infectious diseases caused by Proteus mirabilis comprising the step of administering the bacteriophage to an animal. The method for preventing or treating an infectious disease caused by Proteus mirabilis using the bacteriophage PM2 of the present invention has a very high specificity to Proteus mirabilis as compared with a chemical substance such as existing antibiotics, It has an advantage that it infects Mirabillis and proliferates more than 100 times in the Proteus mirabilis, so that it has excellent lytic activity and is strong against physicochemical stimulation. In addition, the bacteriophage PM2 of the present invention is not infected with any host other than bacteria such as human, animal, and plant, and thus has the advantage of solving problems of antibiotic resistant bacteria caused by abuse of antibiotics, residual antibiotics in food, have. Therefore, the bacteriophage PM2 of the present invention can be variously used in the field of prevention or treatment of infectious diseases caused by Proteus mirabilis, compositions for antibiosis, composition for feed addition, feed, disinfectant, or detergent.
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