K14 Antimicrobial peptide isolated from Bacillus amyloliquefaciens K14 and its use in combinatorial drug therapy

摘要

The present invention relates to a novel Bacillus amyloliquefaciens K14 strain isolated from kimchi, an antimicrobial peptide isolated from the strain, a method for purifying a novel antimicrobial peptide from the strain, and a use of the novel antimicrobial peptide. The antimicrobial peptide (CSpK14) isolated and purified from Bacillus amyloliquefaciens of the present invention not only has a proper antimicrobial effect against MDR pathogens but also CSpK14 significantly increases its activity when it is combined with? -Lactam, Can be usefully used in combination therapies.