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Two-photon fluorescent probe for detection of Cysteine

机译:用于检测半胱氨酸的双光子荧光探针

摘要

The present invention relates to a two-photon fluorescent probe compound represented by the following formula (1) for selectively recognizing cysteine by distinguishing between homocysteine and glutathione in living cells and tissues. The two- It has permeability and low photo-cytotoxicity. TPM can selectively identify cysteine distribution in living tissues without interfering with other biologically relevant substances. It can be used as an effective tool for recognition of intracellular cysteine, RTI ID = 0.0 and / or / RTI [Chemical Formula 1]
机译:本发明涉及一种由下式(1)表示的双光子荧光探针化合物,用于通过区分活细胞和组织中的高半胱氨酸和谷胱甘肽来选择性地识别半胱氨酸。两者具有渗透性和低的光细胞毒性。 TPM可以选择性地识别生物组织中的半胱氨酸分布,而不会干扰其他生物学相关的物质。它可以用作识别细胞内半胱氨酸,和/或/ [化学式1]的有效工具。

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