PHARMACEUTICAL COMPOSITION COMPRISING THE EXTRACTION OF MORINGA OLEIFERA ROOT AS AN EFFECTIVE COMPONENT FOR PREVENTION OR TREATMENT OF THROMBOSIS AND HEALTH FUNCTIONAL FOOD COMPRISING THE SAME

摘要

The present invention relates to a pharmaceutical composition and a health functional food for the prevention or treatment of thrombosis containing an extract from the lower part of Moringa oleifera as an active ingredient. More particularly, Or a pharmaceutical composition and health composition for prevention or treatment / improvement of thrombosis through inhibition of blood coagulation and inhibition of platelet aggregation, comprising hexane fraction, ethyl acetate fraction, butanol fraction or a mixture thereof as an active ingredient, Functional foods. The pharmaceutical composition for the prevention or treatment of thrombosis according to the present invention and the extract of Moringa underground as an active ingredient of the health functional food exhibit excellent thrombogenic activity by the inhibition of thrombogenic enzyme and inhibition of blood coagulation factor, In particular, it has excellent hemostatic activity against human erythrocytes, which is a problem in the moringa topoisomerase extract, has excellent thermal stability, and has an acidic condition of pH 2 and anti-thrombosis activity in plasma, It is expected that it can be used for prevention and treatment of thrombosis such as ischemic stroke and hemorrhagic stroke through improvement of blood circulation and the active ingredient is processed into various forms such as extract, powder, ring, tablet, etc. Excellent formulations that can be taken at any time It is a very useful invention in the pharmaceutical industry and the food industry.