MANUFACTURING METHOD OF SOFT TISSUE FILLER COMPOSITION BASED ON HYALURONIC ACID

摘要

The present invention relates to a soft tissue filling composition chemically crosslinked with hyaluronic acid and hydroxyapatite. More particularly, the present invention relates to a soft tissue filling composition comprising hydroxyapatite, which is an inorganic component derived from a living body, And a manufacturing method thereof. The hyaluronic acid-based soft tissue filling composition according to the present invention increases the production of collagen and increases the elastic modulus (G ') of the hyaluronic acid particles, thereby increasing the volume retention capacity and sustaining capacity of the body by mounting the hydroxyapatite including the bio- It can be used as a damaging agent for repairing skin and tissues, a biomaterial, and a filler that can be injected into the soft tissues in the human body, as it improves the tyndall effect.