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miR-34a CA miR-130a CT Association of miR-34a CA and miR-130a CT SNP with the risk of ischemic stroke in a Korean population

机译:miR-34a CA miR-130a CT在韩国人群中,miR-34a CA和miR-130a CT SNP与缺血性中风的风险相关

摘要

The present invention relates to the relationship between the risk of ischemic stroke in Koreans and the microarray a polymorphism. Specifically, in order to provide information necessary for predicting the risk of ischemic stroke in Korean, miR-34a C A method for identifying a single base polymorphism selected from among A rs6577555, miR-130a C T (rs731384), miR-150 G A (rs73056059) and miR-155 T A (rs767649) (Rs6577555) and miR-150 G A (rs73056059) from a subject's DNA sample to provide information necessary for predicting prognosis, and a kit therefor . According to the present invention, based on the above-mentioned four miRNA polymorphisms, it is possible to predict the risk of ischemic stroke in Korean and to provide useful information for predicting the prognosis. In particular, when the kit of the present invention is used, the above information can be provided more easily.
机译:本发明涉及韩国人缺血性中风的风险与微阵列多态性之间的关系。具体而言,为了提供预测韩文缺血性卒中风险所必需的信息,miR-34a CA方法用于识别选自A rs6577555,miR-130a C> T(rs731384),miR-150 G>的单碱基多态性A(rs73056059)和miR-155 T> A(rs767649)(Rs6577555)和miR-150 G> A(rs73056059)来自受试者的DNA样品,以提供预测预后所需的信息,以及用于该试剂盒的试剂盒。根据本发明,基于上述四个miRNA多态性,可以预测韩国人缺血性中风的风险并提供用于预测预后的有用信息。特别地,当使用本发明的试剂盒时,可以更容易地提供上述信息。

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