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RNA Plasma MicroRNAs for The Detection of Early Colorectal Cancer

机译:RNA血浆MicroRNA用于检测早期大肠癌

摘要

The present invention relates to a colorectal neoplasia diagnosis or detection method, a biomarker, or a diagnostic kit for human, which comprises administering to a subject in need thereof one or more microRNAs in a biological sample of a subject suspected of having colorectal neoplasia MiR19a, miR19b, or miR19a of the microRNAs, including a general expression pattern for the microRNAs and a biomarker for comparing and measuring the overall expression pattern for one or more microRNAs in a normal subject biological sample, And the overexpression of a combination of miR19b and miR15b is indicative of a colorectal cancer.
机译:本发明涉及用于大肠癌的诊断或检测方法,生物标志物或用于人的诊断试剂盒,其包括向有此需要的受试者施用疑似患有大肠赘生物MiR19a的受试者的生物样品中的一种或多种微小RNA, microRNA的miR19b或miR19a,包括该microRNA的一般表达模式和用于比较和测量正常受试者生物学样品中一个或多个microRNA总体表达模式的生物标记,并且miR19b和miR15b的组合的过表达为指示大肠癌。

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