A method of producing biocement based on calcium carbonate to fill bone defects

摘要

FIELD: medicine.SUBSTANCE: invention relates to medicine, specifically to ceramic and cement materials, and discloses a method for producing calcium carbonate-based biocement for filling bone defects. Method is characterized by that the cement grout is obtained by successively adding an additive to the suspension, then the suspension and additives are mixed for 0.5-1 minutes, then calcium carbonate powder is added to the resulting mixture with constant stirring for 1-2 minutes until a uniform cement grout is obtained with a specially selected ratio of components. Resulting cement grout takes 3-8 minutes to form a cement stone, it consists of crystalline phases - calcite and dicalcium phosphate, as well as amorphous calcium phosphate; obtained cement stone is characterized by porosity of 40-70%, a pore size of 500-2,000 μm, and strength of at least 4 MPa.EFFECT: invention can be used for plastic reconstruction of damaged bone tissue.1 cl, 1 tbl, 1 ex