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METHOD AND DEVICE FOR ANALYSIS OF THE BEHAVIOR OF SUBSTANCES IN VITRO IN A SIMULATED PHYSIOLOGICAL ENVIRONMENT
METHOD AND DEVICE FOR ANALYSIS OF THE BEHAVIOR OF SUBSTANCES IN VITRO IN A SIMULATED PHYSIOLOGICAL ENVIRONMENT
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机译:在模拟的生理环境中体外物质行为分析的方法和装置
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摘要
The invention refers to an in vitro method and apparatus for analysing the behaviour of substances in simulated physiological environment. The method comprises the steps of providing a first fluid, a gel matrix and a second fluid, separating the first fluid and the gel matrix by at least one first semi-permeable membrane and separating the gel matrix and the second fluid by at least one second semi-permeable membrane. The method further comprises the steps of injecting a substance into the first fluid, letting the substance migrate from the first fluid through the at least one first semi-permeable membrane, through the gel matrix, through the at least one second semi-permeable membrane and into the second fluid, and determining clearance of the substance from the first fluid.
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