METHOD FOR ESTIMATION OF EFFECTIVENESS OF IMPACT OF CHEMOTHERAPEUTIC PRECAUTIONS OF XENOGRAFT MODEL IN VIVO

摘要

FIELD: medicine.;SUBSTANCE: method involves application of a xenograft model in vivo. Tumour fragments isolated from the patient are used as the transplant. Transplantation performed in the anterior chamber of the rabbit's eye. Doxorubicin or cisplatin are used as chemotherapeutic agents. Constant visual assessment of transplanted cells response to the action of cytostatics is carried out, in particular, continuous analysis of photos of the transplanted tumour.;EFFECT: ability to monitor the processes in the tumour in real time, and react promptly by adjusting treatment.;9 dwg, 1 tbl