ORAL ANTITUMOUR DRUGS AND METHOD FOR ONCOLOGICAL DISEASES TREATMENT

摘要

FIELD: pharmacology.;SUBSTANCE: group of inventions is an oral agent for oncological diseases treatment, comprising: a therapeutically effective amount of (S)-3-[(3-amino-1-pyrrolidinyl)carbonyl]-4,11-dihydroxy-2-methylanthra[2,3-b]furan-5,10-dione, represented by the formula: and a liquid pharmaceutically acceptable carrier comprising one or more solvents selected from water, polyethylene glycol, 1,2-polypropylene glycol, ethanol, glycerol. The oral agent may be a solid dispersion. The group of inventions includes a method for treatment of an oncological disease, comprising oral administration of a therapeutically effective amount of the described agent to a patient in need.;EFFECT: pharmaceuticals according to the invention provide high solubility of anthrafuran, rapid release of the active ingredient from pills or capsules, are stable during storage.;13 cl, 1 dwg, 8 tbl, 7 ex