首页> 外国专利> METHOD OF PREDICTION RISK OF ADVERSE CARDIOVASCULAR AND CEREBROVASCULAR EVENTS FOR 6 YEARS AFTER SCHEDULED ENDOVASCULAR MYOCARDIUM REVASCULARIZATION

METHOD OF PREDICTION RISK OF ADVERSE CARDIOVASCULAR AND CEREBROVASCULAR EVENTS FOR 6 YEARS AFTER SCHEDULED ENDOVASCULAR MYOCARDIUM REVASCULARIZATION

机译:预测的心内膜心肌重构后6年心血管和脑血管异常事件的预测方法

摘要

FIELD: medicine.;SUBSTANCE: following clinical characteristics are determined for the patient: presence or absence of a hereditary predisposition to the development of cardiovascular diseases (x1); percutaneous coronary interventions with statin intake or without it (x2); initial level of postprandial glucose in blood in mmol/l (x3); presence or absence of a high risk of contrast-induced nephropathy development (x4). The probability of risk is calculated by the formula: P = eF/(1+eF). At that, P is the probability of adverse cardiovascular and cerebrovascular events development within 6 years after scheduled percutaneous coronary interventions; e is the base of the natural logarithm (e=2.7183); F is the calculated value of the function, equal to F(x)=b0+b1⋅x1+b2⋅x2+b3⋅x3+b4⋅x4. If P is less than 0.56, a high risk of adverse cardiovascular and cerebrovascular events is predicted within 6 years after scheduled endovascular myocardium revascularization. If P≥0.56, the course of the disease after endovascular intervention on the coronary arteries is favourable.;EFFECT: method allows to predict the onset of adverse cardiovascular and cerebrovascular events within 6 years after scheduled endovascular myocardium revascularization, which ensures timely use of more active follow-up and treatment strategies.;2 tbl
机译:领域:医学。实质:为患者确定以下临床特征:是否存在遗传性易患心血管疾病(x 1 );接受或不接受他汀类药物(x 2 )的经皮冠状动脉介入治疗;血液中餐后血糖的初始水平,以mmol / l(x 3 )为单位;存在或不存在造影剂诱发的肾病发展的高风险(x 4 )。风险概率由以下公式计算:P = e F /(1 + e F )。在此,P是在计划的经皮冠状动脉介入治疗后6年内发生不良心血管和脑血管事件的可能性; e是自然对数的底数(e = 2.7183); F是函数的计算值,等于F(x)= b 0 + b 1 ⋅x 1 + b 2 ⋅x 2 + b 3 ⋅x 3 + b 4 ⋅x 4 。如果P小于0.56,则在计划的血管内心肌血运重建后的6年内,预计发生心血管和脑血管不良事件的高风险。如果P≥0.56,则对冠状动脉进行腔内干预后的病程是有利的;效果:该方法可以预测计划内的腔内心肌血运重建后6年内不良心血管和脑血管事件的发生,从而确保及时使用更多积极的随访和治疗策略。; 2 tbl

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