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METHOD FOR PREDICTION OF PREGNANCY IN IN VITRO FERTILIZATION

机译:体外受精妊娠的预测方法

摘要

FIELD: medicine.;SUBSTANCE: invention relates to such fields of medicine as obstetrics, gynecology and reproductology and is a method for prediction of pregnancy rate through in vitro fertilization with selective embryo transfer. Method is that that biochemical studies for determining the level of magnesium (Mg2+) and zinc (Zn2+) ions in the blood serum (BS), obtained from venous blood, which is sampled in fasting state before puncture of follicles on the day of puncture, and a follicular fluid (FF) containing an oocyte-cumulus complex, obtained by transvaginal puncture of follicles under the control of ultrasound, after which the values of the canonical linear discriminant function (CLDF) are calculated by the formula CLDF = 23.44 * Mg2+BS + 3.45 * Zn2+BS + 49.94 * Mg2+FF + 5.65 * Zn2+FF,and if a value of CLDF is ≥140.94, prognosis of pregnancy is favorable.;EFFECT: invention is simple and it allows to give recommendations on treatment of female infertility for pregnancy in the in vitro program.;1 cl, 1 tbl, 1 dwg, 2 ex
机译:用于胚胎移植的体外受精预测妊娠率的方法技术领域本发明涉及产科,妇科和生殖医学等医学领域,并且是通过体外受精和选择性胚胎移植来预测妊娠率的方法。方法是通过生化研究确定从静脉中获得的血清(BS)中镁(Mg 2 + )和锌(Zn 2 + )离子的水平穿刺当天在穿破卵泡之前以空腹状态采样的血液和含有卵母细胞-卵丘复合物的卵泡液(FF)在超声波的控制下经阴道穿刺穿刺获得,之后的典范线性判别函数(CLDF)由公式CLDF = 23.44 * Mg 2 + BS + 3.45 * Zn 2 + BS + 49.94 * Mg 2+ FF + 5.65 * Zn 2 + FF,如果CLDF≥140.94,则预后良好。效果:发明简单,可以为治疗提供建议体外试验中女性不孕的妊娠率; 1 cl,1 tbl,1 dwg,2 ex

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