METHODS AND COMPOSITIONS FOR TREATMENT OF ABSTINENCE SYMPTOMS USING NON-SEDATING TRANSDERMAL COMPOSITIONS BASED ON DEXMEDETOMIDINE

摘要

FIELD: medicine.;SUBSTANCE: group of inventions refers to medicine, namely to neurology and psychiatry, and can be used to treat individual^’s abstinence symptoms. Treatment involves applying to the surface of the skin of non-sedating individual, who has the abstinence symptoms, devices for transdermal delivery. This device includes a dexmedetomidine-based composition that contains dexmedetomidine, a pressure-sensitive adhesive and a protective layer, the dexmedetomidine-based composition is formulated to deliver a therapeutically effective amount of dexmedetomidine to treat the individual^’s abstinence symptoms. Device for transdermal delivery of a dexmedetomidine-based composition has also been proposed.;EFFECT: group of inventions provides treatment of the individual’s abstinence symptoms.;22 cl, 21 dwg, 23 tbl, 15 ex