MULTI-FOCI SONICATIONS FOR HYPERTHERMIA TREATMENTS USING MAGNETIC RESONANCE-GUIDED FOCUSSED ULTRASOUND

摘要

FIELD: medicine.;SUBSTANCE: group of inventions relates to medical equipment, namely to means for hyperthermia treatments using for multi-foci sonications. Mild hyperthermia treatment apparatus includes an imager, which generates a planning image, a phased array of ultrasonic transducers, an array of ultrasonic transducer drivers for individually driving the ultrasonic transducers of the phased array to generate multi-foci sonications in the target region, one or more processors programmed to receive a target temperature profile based on the planning image, and calculate power, frequency and relative phase for the transducer drivers of the ultrasonic transducer driver array which can cause the phased array of ultrasonic transducers to generate a multi-foci sonication pattern configured to heat the target region with the target temperature profile, calculate the powers, frequencies, and relative phases and/or a number of foci such that the multi-foci sonication profile maintains acoustic pressures in the target region below maximum acoustic pressures. Treatment method is carried out by means of a device.;EFFECT: use of inventions provides lower peak acoustic pressures in the heated region.;15 cl, 9 dwg