METHOD FOR PREDICTING BREAST CANCER RECURRENT DURING ENDOCRINE TREATMENT

摘要

FIELD: biochemistry.;SUBSTANCE: invention relates to biochemistry, in particular to a method for predicting the breast cancer outcome in an estrogen-receptor-positive and HER2-negative tumor in a patient with breast cancer, which involves determining in the tumor sample of the patient the expression level of RNA genes UBE2C, BIRC5, DHCR7, STC2, AZGP1, RBBP8, IL6ST and MGP or genes UBE2C, RACGAP1, DHCR7, STC2, AZGP1, RBBP8, IL6ST and MGP, mathematical combination of values of expression levels, where a higher composite indicator indicates a worse prognosis for said patient compared to a lower composite indicator.;EFFECT: invention allows to effectively predict the breast cancer outcome.;10 cl, 3 dwg, 10 tbl