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PHARMACEUTICAL COMPOSITION FOR NATIONAL ADMINISTRATION

机译:国家行政管理部门的药品成分

摘要

FIELD: medicine; pharmaceuticals.;SUBSTANCE: pharmaceutical composition for nasal administration comprises a complex of active components based on diphenhydramine hydrochloride, zinc sulfate and a water-soluble vasoconstrictor and a complex of auxiliary components comprising an isotonic agent, pH adjusting agent, a pharmaceutically acceptable gelling agent, a quaternary ammonium compound preservative and distilled water in the amounts indicated in the claims. As a vasoconstrictor, the composition comprises xylometazoline hydrochloride or phenylephrine hydrochloride. As a gelling agent, it contains carboxymethylcellulose or hydroxypropylmethylcellulose. As a preservative, the composition contains benzalkonium chloride or dodecyldimethylbenzylammonium chloride. As an isotonic agent, it contains sodium chloride or sodium hydrogencarbonate. As an agent regulating the pH of the aqueous phase, it contains sodium citrate, citric acid or sodium hydrochloride.;EFFECT: composition of the invention is characterized by high therapeutic efficacy and accelerates the epithelialization process of the nasal mucosa.;8 cl, 4 ex
机译:领域:医学;药物:用于鼻腔给药的药物组合物包含基于盐酸苯海拉明,硫酸锌和水溶性血管收缩剂的活性成分的复合物,以及包含等渗剂,pH调节剂,药学上可接受的胶凝剂的辅助成分的复合物,权利要求中指出的量的季铵化合物防腐剂和蒸馏水。作为血管收缩剂,该组合物包含盐酸噻唑啉或盐酸去氧肾上腺素。作为胶凝剂,它包含羧甲基纤维素或羟丙基甲基纤维素。作为防腐剂,该组合物包含苯扎氯铵或十二烷基二甲基苄基氯化铵。作为等渗剂,它包含氯化钠或碳酸氢钠。作为调节水相pH值的试剂,它包含柠檬酸钠,柠檬酸或盐酸钠。效果:本发明的组合物的特征在于高治疗功效并加速了鼻粘膜的上皮形成过程; 8 cl,4前

著录项

  • 公开/公告号RU2657419C1

    专利类型

  • 公开/公告日2018-06-13

    原文格式PDF

  • 申请/专利权人 ANISIMOV SERGEJ NIKOLAEVICH;

    申请/专利号RU20170106801

  • 发明设计人 ANISIMOV SERGEJ NIKOLAEVICH (RU);

    申请日2017-03-01

  • 分类号A61K31/4174;A61K31/137;A61K33/30;A61K47/38;A61K47/18;A61K47;A61K9/08;A61P37/08;A61P27/14;

  • 国家 RU

  • 入库时间 2022-08-21 12:35:33

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