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INACTIVATED EMULSION VACCINE AGAINST FOOT-AND-MOUTH DISEASE TYPE O

机译:灭活的O型口蹄疫乳化疫苗

摘要

FIELD: biotechnology.;SUBSTANCE: invention relates to biotechnology. Invention is an inactivated emulsion vaccine against foot and mouth disease type O. Vaccine contains an avirulent and purified antigenic material from strain O No. 2311/Zabaikalsky/2016 of foot and mouth disease virus obtained in a suspension continuous cell line from the kidney of a newborn golden hamster (BHK-21/2-17 (baby hamster kidney)), which is a suspension containing mainly 146S immunogenic components of the foot and mouth disease virus, oil adjuvants Montanide ISA-70 or Montanide ISA-206 in effective ratios.;EFFECT: vaccine has a high immunogenicity and is able to provide effective protection against the homologous pathogen of the infection circulating in Central and South-East Asia.;10 cl, 10 ex, 1 dwg, 11 tbl
机译:技术领域:本发明涉及生物技术。本发明是针对O型口蹄疫的灭活的乳剂疫苗。该疫苗含有来自口蹄疫病毒的O. 2311 / Zabaikalsky / 2016 O型口蹄疫病毒的无毒和纯化的抗原材料,该菌株是从甲状旁腺的肾脏悬浮的连续细胞系中获得的。新生黄金仓鼠(BHK-21 / 2-17(婴儿仓鼠肾脏)),是一种悬浮液,主要包含有效比例的口蹄疫病毒的146S免疫原性成分,油佐剂Montanide ISA-70或Montanide ISA-206。效果:疫苗具有很高的免疫原性,能够对中亚和东南亚流行的感染的同源病原体提供有效的保护。; 10 cl,10 ex,1 dwg,11 tbl

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