DERIVATIVE OF THE CLASS OF N-GLYCOSIDES INDOLO2,3-APYRROLO3,4-CCARBAZOLE-5,7-DIONE - N-{12-(β-D-XYLOPYRANOSYL)-5,7-DIOXO-INDOLO2,3-APYRROLO3,4-CCARBAZOL-6-YL} PYRIDINE-2-CARBOXAMIDE, WHICH HAS CYTOTOXIC AND ANTITUMOR ACTIVITY

摘要

FIELD: pharmaceuticals.;SUBSTANCE: invention relates to use of the indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione N-glycoside derivative – N-{12-(β-D-xylopyranosyl)-5,7-dioxo-indolo[2,3-a]pyrrolo[3,4-c]carbazol-6-yl}pyridine-2-carboxamide as a compound having antitumor activity for the treatment of mice with adenocarcinoma of the mammary gland Ca 755, epidermoid carcinoma of Lewis lungs, melanoma B16, cervical cancer, adenocarcinoma of the colon ACTOL, Ehrlich tumor in therapeutic doses.;EFFECT: new application of a known biologically active compound has been proposed.;1 cl, 3 tbl, 1 ex