A method of estimating shear modulus and viscosity of tissue of a patient based on shear wave images of the tissue, the method comprising: simulating shear wave propagation in the tissue based on shear modulus and viscosity values for the tissue using a tissue A model of shear wave propagation, comparing the simulated shear wave propagation with the observed shear wave propagation in the shear wave images of the tissue using a cost function, estimating patient specific shear modulus and tissue viscosity values, the cost function the simulated Shear wave propagation with the observed shear wave propagation compares, optimizes, and calculates a cost function in a high frequency space containing a measured high frequency shift of the observed shear wave propagation with a calculated high frequency shift of the simulated Shear wave propagation compares.
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