首页> 外国专利> EXTRACT OF PHALERIA MACROCARPA AS AN ANTINEOPLASTIC, ANTI-INFLAMMATORY AND ANTIANGIOGENIC AGENT

EXTRACT OF PHALERIA MACROCARPA AS AN ANTINEOPLASTIC, ANTI-INFLAMMATORY AND ANTIANGIOGENIC AGENT

机译：抗菌药物提取物作为抗肿瘤，抗炎和抗血管生成剂

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摘要

A pharmaceutical dosage form comprising an extract of Phaleria macrocarpa which has antineoplastic, anti-inflammatory, and antiangiogenic activity. Its use as an antineoplastic agent is to inhibit tumour growth. Its use as an anti-inflammatory agent is to relieve inflammation and pain, and also as an antipyretic. Another use is as an antiangiogenic agent to inhibit the growth of new blood vessels to prevent cancer metastasis.

机译：一种药物剂型，其包含具有抗肿瘤，抗炎和抗血管生成活性的大鸡蛋花提取物。它作为抗肿瘤药的用途是抑制肿瘤的生长。它用作抗炎药可缓解炎症和疼痛，也可作为退烧药。另一个用途是用作抗血管生成剂，以抑制新血管的生长，从而防止癌症转移。

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公开/公告号EP2310027B1

专利类型
公开/公告日2019-09-11

原文格式PDF
申请/专利权人 PT. DEXA MEDICA;
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申请/专利号EP20090766229
发明设计人 TJANDRAWINATA RAYMOND R.;ARIPIN ASEP;ARIFIN POPPY FIRZANI;RAHMI DINA;
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申请日2009-06-08
分类号A61K36/83;A61P35;
国家 EP
入库时间 2022-08-21 12:31:55

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2. Isolation and identification of compounds from Phaleria macrocarpa(Scheff.) Boerl fruit extract [J] . Emanuel Dani Ramdani, Ujiatmi Dwi Marlupi, James Sinambela, 亚太热带生物医学杂志：英文版 . 2017,第004期

3. Inhibition of Mahkota Dewa (Phaleria macrocarpa) bioactive fraction on proliferation of human retinoblastoma tumor cells Y-79 through suppression of mRNA level of cyclin E [J] . Nugroho Trilaksana, Ignatius Riwanto, Raymond Rubianto Tjandrawinata, 亚太热带生物医学杂志（英文版） . 2017,第004期

4. Inhibition of Mahkota Dewa(Phaleria macrocarpa) bioactive fraction on proliferation of human retinoblastoma tumor cells Y-79 through suppression of mRNA level of cyclin E [J] . Nugroho Trilaksana, Ignatius Riwanto, Raymond Rubianto Tjandrawinata, 亚太热带生物医学杂志：英文版 . 2017,第004期

5. Standardized bioactive fraction of Phaleria macrocarpa (Proliverenol) prevents ethanol-induced hepatotoxicity via down-regulation of NF-kB-TNFα-caspase-8 pathway [J] . Guntur Berlian, Olivia Mayasari Tandrasasmita, Raymond Rubianto Tjandrawinata 亚太热带生物医学杂志（英文版） . 2016,第008期

6. Anti-inflammatory, antiangiogenic, and apoptosis-inducing activity of DLBS1442, a bioactive fraction of Phaleria macrocarpa, in a RL95-2 cell line as?a?molecular model of endometriosis [J] . Olivia M Tandrasasmita, Adeline M Sutanto, Poppy F Arifin, International Journal of Women s Health . 2015,第1期

7. Anti-inflammatory Activity of the Major Compound from Methanol Extract of Phaleria macrocarpa Leaves [J] . I. Nor Fariza, J. Fadzureena, A. Zunoliza, Journal of Applied Sciences . 2012,第11期

8. Anti-inflammatory Activity of the Major Compound from Methanol Extract of Phaleria macrocarpa Leaves [J] . I. Nor Fariza, J. Fadzureena, A. Zunoliza, Journal of Applied Sciences . 2012,第11期

9. Effectiveness of Mahkota Dewa Fruit Extract ((Phaleria Macrocarpa (Scheff.) Boerl)) With Various Concentration of Methanol Solutions on Aedes Aegypti Larva Mortality [C] . Farindira Vesti Rahmasari, Aferita Sari International Integrative Conference on Health, Life and Social Sciences . 2018

10. Antiangiogenic agents from Tripterygium wilfordii for cancer treatment. [D] . He, Mingfang. 2009

11. Anti-inflammatory antiangiogenic and apoptosis-inducing activity of DLBS1442 a bioactive fraction of Phaleria macrocarpa in a RL95-2 cell line as a molecular model of endometriosis [O] . Olivia M Tandrasasmita, Adeline M Sutanto, Poppy F Arifin, 2015

12. Anti-inflammatory, antiangiogenic, and apoptosis-inducing activity of DLBS1442, a bioactive fraction of Phaleria macrocarpa, in a RL95-2 cell line asnbsp;anbsp;molecular model of endometriosis [O] . Raymond Tjandrawinata, Olivia Tandrasasmita, Adeline Sutanto, 2015

13. Toxicity of Divided Doses of Antineoplastic Agents in Mice and Their Antineoplastic Effect in L-1210 Inoculated Mice. [R] . zendzian,robert p. teeters, winnie r. 1971

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