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SPECIFIC DETECTION TOOL FOR MESENCHYMAL AND EPITHELIAL-MESENCHYMAL TRANSFORMED CIRCULATING TUMOR CELLS
SPECIFIC DETECTION TOOL FOR MESENCHYMAL AND EPITHELIAL-MESENCHYMAL TRANSFORMED CIRCULATING TUMOR CELLS
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机译:间质和上皮间质转化循环肿瘤细胞的特异性检测工具
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摘要
The present invention includes the discovery of cell-surface vimentin as a novel biomarker to detect and isolate mesenchymal and epithelial-mesenchymal transformed circulating tumor cells from blood of cancer patients. In addition, an antibody specific for the detection of cell-surface vimentin on circulating tumor cells and the use the antibody to detect, enumerate, and isolate CTC are provided.
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