首页> 外国专利> METHOD FOR PREPARING CABAZITAXEL FROM 10-DEACETYLBACCATIN III IN HIGH YIELD, AND NOVEL INTERMEDIATE THEREFOR

METHOD FOR PREPARING CABAZITAXEL FROM 10-DEACETYLBACCATIN III IN HIGH YIELD, AND NOVEL INTERMEDIATE THEREFOR

机译:高产10-乙酰基酪蛋白Ⅲ制备卡巴他赛的方法及新型中间体

摘要

The present invention relates to a novel method for preparing cabazitaxel from 10-deacetylbaccatin III, and a novel intermediate therefor, and more specifically, to: a method which allows cabazitaxel to be more easily prepared in a high yield and in a high purity within a short time compared with a conventional method by preparing cabazitaxel via a novel intermediate using 10-deacetylbaccatin III as a starting material, and thus is suitable for industrial mass production; and a novel intermediate therefor.
机译:本发明涉及一种由10-去乙酰基浆果赤霉素Ⅲ制备卡巴他赛的新方法,及其新的中间体,更具体地,涉及一种使卡巴他赛更容易以高收率和高纯度制备的方法。与通过以10-脱乙酰基浆果赤霉素III为起始原料的新型中间体制备卡巴他赛的方法相比,时间短,因此适于工业批量生产。及其新的中间体。

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