METHOD USING EXPRESSION OF LIN28 FOR PREPARING STEM CELL HAVING EXCELLENT RENEWAL ABILITY AND DIFFERENTIATION POTENCY

摘要

The present invention relates to a cell therapeutic agent comprising a stem cell expressing Lin28, a pharmaceutical composition comprising a neural stem cell expressing Lin28 for the prevention or treatment of a neurological disorder, and a method for treating a neurological disorder using the composition. A stem cell superior in terms of differentiation potency to various tissue cells and renewal ability can be prepared by introducing Lin28, which regulates an embryonic development procedure, or a vector expressing Lin28 during stem cell culturing, and by culturing the cell.