N-MYRISTOYLTRANSFERASE (NMT)1, NMT2 AND METHIONINE AMINOPEPTIDASE 2 OVEREXPRESSION IN PERIPHERAL BLOOD AND PERIPHERAL BLOOD MONONUCLEAR CELLS IS A MARKER FOR ADENOMATOUS POLYPS AND EARLY DETECTION OF COLORECTAL CANCER

摘要

Described herein is the identification of the NMT1, NMT2 and metAP2 genes, mRNA overexpressed in PBMCs of patients with adenomatous polyps in comparison with patients with non-adenomatous polyps and healthy controls. We also discovered that NMT2 levels are higher in the PBMCs of patients adenomatous polyps in comparison with patients with non-adenomatous polyps and healthy control subjects.