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LIQUID FORMULATIONS OF CELECOXIB FOR ORAL ADMINISTRATION

机译:塞来昔布口服制剂

摘要

The invention provides pharmaceutical preparations of celecoxib in suspension, solution, and combination thereof for oral administration. Insolubility of celecoxib in water is overcome in embodiments of the invention by employing co-solvents, and liquid dosage forms having celecoxib in solution at concentrations up to 10 mg/ml are provided. Manufacturing methods for celecoxib suspensions are included in the present disclosure.
机译:本发明提供了用于口服给药的塞来昔布悬浮液,溶液及其组合的药物制剂。在本发明的实施方案中,通过使用助溶剂克服了塞来昔布在水中的不溶性,并且提供了在溶液中具有高达10mg / ml浓度的塞来昔布的液体剂型。塞来昔布悬浮液的制造方法包括在本公开中。

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