ENAHNCED ORAL ABSORPTION OF CELECOXIB IN HUMAN SUBJECTS FROM SELF-EMULSIFYING ORAL DELIVERY SYSTEM

摘要

In this study different surfactants, co-emulsifiers and oils were evaluated in producing a self-emulsifying system (SES). Selected formulae with dissolved celecoxib had shown improve in dissolution rate and oral absorption compared to conventional capsules. This indicates the possibility of using such systems to improve Celecoxib bioavailability.