DETECTION OF CANCER BIOMARKERS USING NANOPARTICLES

摘要

The present invention relates to methods for identifying and detecting potential disease specific biomarkers from biofluids. In particular, the methods involve in vivo administration of nanoparticles to a subject in a diseased state or incubating nanoparticles in a biofluid sample taken from a subject in a diseased state and analysis of the biomolecule corona formed on said nanoparticles. In addition, the present invention also relates to methods that provide a means to distinguish between a healthy and diseased state in a subject, such as for example the presence of a tumor in a human subject.