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METHODS OF TREATMENT FOR CANDIDA AURIS INFECTIONS

机译：念珠菌感染的治疗方法

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摘要

Disclosed herein are compositions and methods for treating and immunizing against C. auris infection and colonization. The compositions and methods include polypeptides and fragments derived from the C. albicans Als3 protein, homologs thereof, and antibodies or fragments thereof that specifically bind these polypeptides and fragments. Administration of these compositions confers treatment and resistance against C. auris infection and colonization.

机译：本文公开了用于治疗和免疫 C 的组合物和方法。 auris 感染和定植。所述组合物和方法包括衍生自 C 的多肽和片段。白色念珠 Als3蛋白，其同源物以及与这些多肽和片段特异性结合的抗体或其片段。这些组合物的施用赋予了对 C 的治疗和抵抗力。 auris 感染和定植。 展开▼

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公开/公告号EP3552620A1

专利类型

公开/公告日2019-10-16

原文格式PDF

申请/专利权人 LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER;
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申请/专利号EP20180166876

发明设计人 EDWARDS JR. JOHN E.;SINGH SHAKTI;UPPULURI PRIYA;IBRAHIM ASHRAF S.;
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申请日2018-04-11

分类号A61K39;C07K16/14;

国家 EP

入库时间 2022-08-21 12:28:57

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