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THERAPEUTIC AGENT FOR ANEMIA INCLUDING RENAL ANEMIA AND CANCER-INDUCED ANEMIA WHICH CONTAINS ANTI-BMP9 ANTIBODY AS ACTIVE INGREDIENT
THERAPEUTIC AGENT FOR ANEMIA INCLUDING RENAL ANEMIA AND CANCER-INDUCED ANEMIA WHICH CONTAINS ANTI-BMP9 ANTIBODY AS ACTIVE INGREDIENT
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机译:含有ANTI-BMP9抗体作为活性成分的治疗贫血的血液病治疗剂,包括肾病和癌性贫血
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摘要
The present invention provides an anti-BMP9 (Bone morphogenetic protein-9) monoclonal antibody or an antibody fragment thereof binding to human BMP9, a hybridoma producing the antibody or the antibody fragment, a DNA encoding the antibody or the antibody fragment, a vector comprising the DNA, a transformant obtained by introduction of the vector, a method for preparing the antibody or the antibody fragment using the hybridoma or the transformant, and a therapeutic agent comprising the antibody or the antibody fragment as an active ingredient. Further, the present invention provides a pharmaceutical composition comprising the antibody or the antibody fragment as an active ingredient for the treatment of anemia such as renal anemia, cancer anemia or the like, and a method for treating anemia such as renal anemia, cancer anemia or the like using the same.
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