首页>
外国专利>
METHOD FOR CONVERTING MONOCOT PLANT GENOME SEQUENCE IN WHICH NUCLEIC ACID BASE IN TARGETED DNA SEQUENCE IS SPECIFICALLY CONVERTED, AND MOLECULAR COMPLEX USED THEREIN
METHOD FOR CONVERTING MONOCOT PLANT GENOME SEQUENCE IN WHICH NUCLEIC ACID BASE IN TARGETED DNA SEQUENCE IS SPECIFICALLY CONVERTED, AND MOLECULAR COMPLEX USED THEREIN
展开▼
机译:专门转换目标DNA序列中核酸碱基中单价植物基因组序列的方法,并在其中使用分子复合物
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention provides a method of modifying a targeted site of a double stranded DNA of a monocot cell, comprising a step of contacting a complex wherein a nucleic acid sequence-recognizing module that specifically binds to a target nucleotide sequence in the given double stranded DNA and a nucleic acid base converting enzyme are bonded, with said double stranded DNA, to convert one or more nucleotides in the targeted site to other one or more nucleotides or delete one or more nucleotides, or insert one or more nucleotides into said targeted site, without cleaving at least one strand of said double stranded DNA in the targeted site, wherein the double stranded DNA is contacted with the complex by introducing a nucleic acid encoding the complex into the monocot cell. Furthermore, also provided is a complex used for the method, wherein a nucleic acid sequence-recognizing module that specifically binds to a target nucleotide sequence in a double stranded DNA of a monocot cell and a nucleic acid base converting enzyme are bonded.
展开▼