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ANTIPARKINSON TABLET FORMULATION WITH IMPROVED DISSOLUTION PROFILE
ANTIPARKINSON TABLET FORMULATION WITH IMPROVED DISSOLUTION PROFILE
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机译:改善溶出度的抗帕金森片配方
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摘要
The present invention relates to a process for preparing pharmaceutical fixed dose combination, immediate release tablet comprising levodopa, carbidopa and entacapone or pharmaceutically acceptable salts or hydrates thereof characterized in that Entacapone has very rapidly dissolving property by using low particle size distribution. Also levodopa and carbidopa are granulated together to produce a common granule and entacapone is granulated separatelyin order to facilitate the production of pharmaceutical tablet combination.
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