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COMPOSITE FORMULATION OF DUTASTERIDE AND TADALAFIL COMPRISING GLYCEROL FATTY ACID ESTER DERIVATIVE OR PROPYLENE GLYCOL FATTY ACID ESTER DERIVATIVE AND ORAL CAPSULE FORMULATION COMPRISING THE SAME
COMPOSITE FORMULATION OF DUTASTERIDE AND TADALAFIL COMPRISING GLYCEROL FATTY ACID ESTER DERIVATIVE OR PROPYLENE GLYCOL FATTY ACID ESTER DERIVATIVE AND ORAL CAPSULE FORMULATION COMPRISING THE SAME
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机译:包含甘油脂肪酸酯衍生物或丙二醇脂肪酸酯衍生物和口服胶囊制剂的硬脂酸酯和他达那非的复合制剂
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摘要
The present invention is related to a composite formulation of dutasteride and tadalafil, therapeutic agents for prostatic hyperplasia, and to an oral capsule preparation containing the same. The composite formulation has the total amount of the composition inside a capsule of 400 mg or less so that the size of the capsule is convenient for the patient to take so as to increase patients' convenience, and includes a glycerol fatty acid ester derivative or a propylene glycol fatty acid ester derivative which may increase the solubility of dutasteride, a poorly soluble medicament and improve the stability of tadalafil so as to dissolve dutasteride and disperse tadalafil.
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