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NEW QUINOLINE AND ISOQUINOLINE DERIVATIVES FOR TREATING PAIN AND PAIN RELATED CONDITIONS

机译：用于治疗疼痛和疼痛相关状况的新喹啉和异喹啉衍生物

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摘要

The present invention relates to new compounds of formula (I): showing great affinity and activity towards the subunit ±2´ of voltage-gated calcium channels (VGCC), especially the ±2´-1 subunit of voltage-gated calcium channels or dual activity towards subunit ±2´ of voltage-gated calcium channels (VGCC), especially the ±2´-1 subunit of voltage-gated calcium channels, and the noradrenaline transporter (NET).

机译：本发明涉及式（I）的新化合物：对电压门控钙通道（VGCC）的±2´亚基表现出极大的亲和力和活性，尤其是电压门控钙通道的±2´-1亚基，或者对电压门控钙通道的±2´亚基具有双重活性（ VGCC），尤其是电压门控钙通道的±2´-1亚基和去甲肾上腺素转运蛋白（NET）。

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公开/公告号EP3558965A1

专利类型
公开/公告日2019-10-30

原文格式PDF
申请/专利权人 ESTEVE PHARMACEUTICALS S.A.;
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申请/专利号EP20170822660
发明设计人 ALMANSA-ROSALES CARMEN;YENES-MINGUEZ SUSANA;VIRGILI-BERNADÓ MARINA;ALONSO-XALMA MÓNICA;
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申请日2017-12-20
分类号C07D401/12;C07D405/12;C07D409/02;C07D409/06;C07D417/12;A61K31/47;A61K31/4725;
国家 EP
入库时间 2022-08-21 12:27:32

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