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REPAIRING COMPOUND HETEROZYGOUS RECESSIVE MUTATIONS BY ALLELE EXCHANGE
REPAIRING COMPOUND HETEROZYGOUS RECESSIVE MUTATIONS BY ALLELE EXCHANGE
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机译:通过等位基因交换修复复合的多态旧突变
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摘要
The disclosure in some aspects relates to methods and compositions for repairing mutations (e.g., compound heterozygous mutations) that are widely found in patients having certain diseases (e.g., monogenic recessive diseases). In some aspects, the disclosure provides a method for targeted allelic exchange using recombinant gene editing complex.
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