TREATMENT OF HIPPO PATHWAY MUTANT TUMORS AND METHODS OF IDENTIFYING SUBJECTS AS CANDIDATES FOR TREATMENT

摘要

The present invention relates to a method of treating a tumor in a subject. This method involves administering to a subject having a Hippo pathway mutant tumor a tankyrase inhibitor, where the tumor is susceptible to treatment with the tankyrase inhibitor, and said administering is carried out to treat the tumor. The present invention also relates to a method of treating cancer in a subject, and a method of identifying a subject as a candidate for treatment.