首页> 外国专利> TREATMENT OF LUNG CANCER USING A COMBINATION OF AN ANTI-PD-1 ANTIBODY AND ANOTHER ANTI-CANCER AGENT

TREATMENT OF LUNG CANCER USING A COMBINATION OF AN ANTI-PD-1 ANTIBODY AND ANOTHER ANTI-CANCER AGENT

机译:联合抗PD-1抗体和另一种抗癌药物治疗肺癌

摘要

This disclosure provides a method for treating a subject afflicted with a lung cancer, which method comprises administering to the subject therapeutically effective amounts of: (a) an anticancer agent which is an antibody or an antigen-binding portion thereof that specifically binds to a Programmed Death-1 (PD-1) receptor and inhibits PD-1 activity which can be administered by infusion for less than 60 minutes; and, optionally, (b) another anti-cancer agent which is administered by infusion for less than 90 minutes. The other anti-cancer agent can be an anti- Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4) antibody.
机译:本公开提供了一种用于治疗罹患肺癌的受试者的方法,该方法包括向该受试者施用治疗有效量的:(a)抗癌剂,其是特异性结合程序性抗体的抗体或其抗原结合部分。死亡1(PD-1)受体并抑制PD-1活性,可通过输注少于60分钟来给药; (b)另一种抗癌剂,其通过输注少于90分钟给药。另一抗癌剂可以是抗细胞毒性T淋巴细胞抗原4(CTLA-4)抗体。

著录项

  • 公开/公告号EP3408296A1

    专利类型

  • 公开/公告日2018-12-05

    原文格式PDF

  • 申请/专利权人 BRISTOL-MYERS SQUIBB COMPANY;

    申请/专利号EP20170707430

  • 发明设计人 NATHAN FAITH;

    申请日2017-01-27

  • 分类号C07K16/28;A61K39;

  • 国家 EP

  • 入库时间 2022-08-21 12:25:41

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