USE OF 2-CARBOXAMIDE CYCLOAMINO UREA DERIVATIVES IN TREATMENT OF EGFR DEPENDENT DISEASES OR DISEASES THAT HAVE ACQUIRED RESISTANCE TO AGENTS THAT TARGET EGFR FAMILY MEMBERS

摘要

To provide a method for the treatment of Epidermal Growth Factor Receptor (EGFR) dependent diseases or diseases that have acquired resistance to agents that target EGFR family members.SOLUTION: The present invention provides use of a compound of the following formula for producing pharmaceutical formulations for the treatment of EGFR dependent diseases, or salt thereof (e.g. (S)-Pyrrolidine-1,2-dicarboxylic acid 2-amide 1-({4-methyl-5-[2-(2,2,2-trifluoro-1,1-dimethyl-ethyl)-pyridin-4-yl]-thiazol-2-yl}-amide).SELECTED DRAWING: None