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Peptides, peptide combinations, and cell based drugs for use in immunotherapy against bladder cancer and other cancers

机译:用于针对膀胱癌和其他癌症的免疫疗法的肽,肽组合和基于细胞的药物

摘要

The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapy. In particular, the present invention relates to cancer immunotherapy. The present invention further relates to a tumor associated T cell peptide epitope alone or in combination with other tumor associated peptides, which for example stimulates an anti-tumor immune response or stimulates T cells ex vivo to patients And act as the active pharmaceutical ingredient of the vaccine composition. Peptides bound to molecules of the major histocompatibility complex (MHC), or the peptides themselves, can also be targets for antibodies, soluble T cell receptors, and other binding molecules.
机译:本发明涉及用于免疫疗法的肽,蛋白质,核酸和细胞。特别地,本发明涉及癌症免疫疗法。本发明进一步涉及单独或与其他肿瘤相关肽组合的肿瘤相关T细胞肽表位,其例如刺激患者离体刺激抗肿瘤免疫应答或刺激T细胞并充当其活性药物成分。疫苗成分。与主要组织相容性复合物(MHC)的分子结合的肽或这些肽本身也可以作为抗体,可溶性T细胞受体和其他结合分子的靶标。

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