Peptides, peptide combinations, and cell based agents for use in immunotherapy for bladder cancer and other cancers

摘要

Problem to be solved: to provide peptides, proteins, nucleic acids, and cells for use in immunotherapy, particularly immunotherapy for cancer."Solution" is a tumor associated T cell Petit epitope combined with a single or other tumor associated peptide, which stimulates an antitumor immune response, for example, or stimulates T cells in vitro to transfer it to a patient It can play the role of active pharmaceutical components of vaccine composition.Peptides or peptides themselves bound to molecules in the main histocompatibility complex (MHC) may also be targets of antibodies, soluble T cell receptors, and other binding molecules.Diagram